This book focus on the product design process. It follows a holistic approach covering conceptual design, design methodologies, sustainability, manufacturing, product analysis, materials, design and manufacturing technologies. The reader can find interesting cases about industrial design, 3D printing and 4D printing for wearables. The axiomatic design methodology is presented together with applications in machine learning and knowledge-based systems. Research about personalized fashion and professional uniform evaluations methods are included. Finally, the digital transformation, aesthetic design and the use of materials in orthopedic design is present.